| Integrating
the Discovery Laboratory
Live Q&A session will
immediately follow
One of the greatest challenges facing research
operations is the consolidation of information
from the disparate information silos that have
propagated in the last decade. Not only are
scientists faced with having to access multiple
systems on a daily basis, the facts these systems
contain are often not consolidated, making it
difficult to create new knowledge on compounds
and materials. Coming to the market only recently,
new tools are available to research organization
to build bridges between information islands
and to create an integrated research knowledge
base. Our expert panel will discuss how these
technologies are being used and best practices
for deployment.
Discussion Topics/Panelists:
Simplifying the Scientist’s
Experience in Drug Discovery Informatics
Craig Tulig
Associate Director
Millennium Pharmaceuticals
Drug Discovery is a complex, multifaceted problem
and the informatics systems deployed to support
Discovery have to contend with this complexity
at both the point solution level and more broadly
as one looks across the many Discovery systems
in use. This complexity can be reduced from
the scientific end-user perspective by centralizing
related tools and data and can also be reduced
from the informatics perspective by making appropriate
enterprise architecture decisions. This talk
will cover example centralization points in
the Millennium Drug Discovery platform and touch
on the architectural choices made to achieve
them.
Craig has been with
Millennium for seven years and has run a number
of informatics projects for Millennium’s
Drug Discovery departments. These include Millennium’s
Decision Support system for Drug Discovery,
and more recently, Millennium’s Chemistry
eNotebook initiatives. Prior to Millennium,
Craig worked at Genome Therapeutics where he
was responsible for the company’s technology
platform to support research in Human Genetics.
HE holds engineering degrees from Boston University
and Syracuse University.
Better Scientific
Decision Support and Project Management though
a Collaborative, "Information-centric"
Tool
Daniel Weaver, Ph.D.
Senior Manager of Scientific Systems
Array Biopharmaceuticals
Array is co-developing a collaborative decision
support and project management environment with
General Dynamics VIZ that integrates all the
hard data and human intuition into one interface.
Through this approach, project plans, work progress
and scientific results are updated and disseminated
automatically, and are presented in an interface
that permits and encourages user annotation.
As a result, all relevant data is at hand for
the scientists assessing a project situation
and making well-informed decisions. This talk
will describe why a different approach to scientific
decision support is warranted and will assert
that a collaborative, "information-centric"
environment will drive better project results
by drawing on examples from other industries.
I will present a case study of our progress
and results, and will highlight the architectural
consideration, cultural issues and long-term
prospectus of this new approach to developing
therapeutics.
Daniel Weaver is Senior
Manager of Scientific Computing at Array Biopharma,
where he is responsible for deploying scientific
software solutions to Array’s scientists.
He was previously a Lead Scientist and Project
Manager at Genomica, where he led the gene expression
analysis project and human genetic analysis
software development. Daniel graduated with
a degree in Molecular Biology from Johns Hopkins
University in 1991. He received his Ph.D. in
Developmental Biology and Genetics in 1998 from
the University of Colorado. Daniel joined Genomica
after performing postdoctoral research with
Gary Stormo, Ph.D., investigating mathematical
modeling techniques for gene expression network
analysis.
Moderator:
Michael H. Elliott
President
Atrium Research
Michael H. Elliott
is the founder of Atrium Research and a recognized
expert in the field of laboratory informatics.
He founded the company in 2003 with a mission
to provide in-depth and un-biased information
on informatics markets, technologies, products
and suppliers. He began his 24+ year technology
career began as a clinical research chemist
at the Indiana University Medical Center. In
1983, he joined Perkin-Elmer, a large analytical
instrument and LIMS company (now developed by
ABI), as a laboratory information and automation
technical consultant. His career progressed
into positions that included LIMS sales, IT
project manager, director of U.S. operations,
vice president of worldwide marketing and product
management, and division vice president and
general manager. Later, he joined Scientific
Software (now part of Agilent Technologies),
a large supplier of scientific content management
and laboratory automation software, as senior
vice president responsible for worldwide operations.
He has written landmark research studies on
the ELN and scientific data management markets
and is routinely quoted for his expertise in
major publications. He has presented at conferences,
events and seminars in over 20 countries and
has multiple articles published on laboratory
informatics. Mike also serves on the editorial
board of Scientific Computing magazine.
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